The cancer occurs in the peripheral blood which means that the malignant cells are present in the peripheral blood. Aggressive NK-cell leukemia is a rare malignancy with neoplastic proliferation of natural killer cells. Here we report the case of an ANKL presenting in a young Hispanic male with secondary hemophagocytosis. Abstractor Notes The most common sites of involvement are peripheral bloo bone marrow, liver and spleen however.
The median overall survival (OS) is less than months. The body makes large numbers of NK cells that are larger than normal. Aggressive natural killer cell leukemia (ANKL ) is a rare neoplasm of mature natural killer cells, with an extremely poor overall survival, which is almost always EBV relate with majority of cases reported in East Asia.
Aggressive NK-cell leukemia
Aggressive NK-cell leukemia - Canadian Cancer Society Aggressive NK-cell leukemia (also called aggressive NK-cell lymphoma, or ANKL, is a very rare type of NHL.