Glioma stem cells

Several years ago, the discovery of a highly tumorigenic subpopulation of stem-like cells embedded within fresh surgical isolates of malignant gliomas lent support to a new paradigm in cancer biologythe cancer stem cell hypothesis. Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner D Rich JN. Cancer stem cells in glioblastoma - PubMed Central (PMC) Jun 1 20Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.

Glioma Stem Cells: Signaling, Microenvironment, and Therapy Termed tumor-initiating cells or glioma stem cells (GSCs these neoplastic units possess many common characteristics with normal neural stem cells (NSCs such as the capacity to self-renew, indefinitely proliferate and differentiate into different cell types that originate from the). Significantly, glioma neural stem (GNS) cell lines from different tumors exhibit divergent gene expression signatures and differentiation behavior that correlate with specific neural progenitor subtypes.

The diversity of gliomas may, therefore, reflect distinct cancer stem cell phenotypes. Glioma - Symptoms and causes - Mayo Clinic Jun 2 20Glioma Stem Cells: A Midterm Exam. 2Depression quots Inspirational Sayings on Feeling Down Mar 2 20These quots about depression are meant to help you see the light even in the darkest of times in your life.

A total of 2patients, 1female (46) and 1male (received root canal treatment of maxillary second premolar from January 20to January 2014).
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